Circulating anti- Helicobacter pylori immunoglobulin A anitbodies and low serum pepsinogen I level are associated with increased risk of gastric cancer.
Direct analysis by small-pool PCR of MS205 minisatellite mutation rates in sperm after mutagenic therapies. Berkeley, CA: University of California Press.Īrmour, J.A., M.H. 18-38 in Proceedings of the Fourth Berkeley Symposium on Mathematical Statistics and Probability, Vol. A two-stage theory of carcinogenesis in relation to the age distribution of human cancer. Brit J Cancer 8:1-12.Īrmitage, P., and R. The age distribution of cancer and a multistage theory of carcinogenesis. Second cancer after radiation therapy for cancer of the uterine cervix. Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy.
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes. A locus that influences susceptibility to 1,2-dimethylhydrazine-induced colon tumors maps to the distal end of mouse chromosome 3. Cancer risk among staff at two radiotherapy departments in Denmark. United States Life Tables, National Vital Statistics Reports, Vol. Int J Radiat Biol 76:31-42.Īnderson, R.N., and P.B. Complex chromosome aberrations in peripheral blood lymphocytes as a potential biomarker of exposure to high-LET alpha-particles. Induction of stress genes by low doses of gamma rays. Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses. A comparison of induced mutations at homologous alleles of the tk locus in human cells. Inverse dose-rate effect for mutation induction by gamma-rays in human lymphoblasts. Lethal mutations attributable to misrepair of Q-lesions. Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia. Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43. Rapid screening for deletion mutations in the hprt gene using the polymerase chain reaction: x-ray and alpha-particle mutant spectra. A BrdU pulse double-labelling method for studying adaptive response. Harwell, UK: United Kingdom Atomic Energy Authority.Īghamohammadi, S.Z., and J.R. Authority Health and Safety Branch Report. An Investigation into the Accuracy Attained in Routine Film-Badge Dosimetry at UKAEA Establishments. Mortality among workers at the Pantex weapons facility. Third (fourth and fifth) tumours in survivors of retinoblastoma. When the vertical frequency of isolators reduces to 1 Hz, the rocking effect is obvious and rocking restraining devices are necessary.Abramson, D.H., M.R. Among the studied cases, the case that has a vertical isolation frequency of 3 Hz is the one that can keep the horizontal period of the isolators as the first period while having the most flexible vertical isolator properties. It was found that compared with the general horizontal isolators, isolators that have vertical frequencies of no more than 3 Hz can effectively reduce the vertical in-structure responses for the studied NPP model.
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In particular, a series of case study analyses of a modern NPP model are performed to examine the benefits and challenges associated with 3D isolation compared with horizontal isolation. This paper examines several vertical and 3D isolation systems that have been proposed and their potential application to modern nuclear facilities. As such, there is considerable interest worldwide in vertical and three-dimensional (3D) isolation systems. This issue becomes a great concern to facilities such as a Nuclear Power Plants (NPP), with specialized equipment and machinery that is not only expensive, but critical to safe operation.
Records from instrumented structures, and some recent tests and analyses have actually seen increases in vertical responses in base isolated structures under the combined effects of horizontal and vertical ground motions. Although the horizontal component of an earthquake response can be significantly reduced through the use of conventional seismic isolators, the vertical component of excitation is still transmitted directly into the structure.